Research Scientist - Pannexin 1 Channel Blockers

Job Description

Job Description

Company Overview

Pannex Therapeutics Inc. is an early-stage biopharmaceutical company based in New York City, founded in 2020. The company is pioneering the development of a novel class of small-molecule drugs targeting Pannexin 1 (Panx1) channels. These channels play a crucial role in various disease pathways, including cancer progression and neurological disorders. Pannex Therapeutics aims to deliver safer and more effective treatments for life-threatening conditions such as triple-negative breast cancer (TNBC) and chronic pain.

Position Overview

Pannex Therapeutics is seeking a highly motivated and skilled Research Scientist to join our dynamic team. The successful candidate will play a pivotal role in advancing our drug discovery efforts targeting Panx1 channels. This position offers an exciting opportunity to contribute to the development of first-in-class therapies in a collaborative and innovative environment.

Key Responsibilities

• Drug Discovery & Development: Lead and contribute to the design, synthesis, and optimization of small-molecule inhibitors targeting Panx1 channels.

• Preclinical Studies: Plan and execute in vitro and in vivo experiments to evaluate the efficacy and safety of lead compounds.

• Collaboration: Work closely with cross-functional teams, including medicinal chemistry, pharmacology, and toxicology, to advance drug candidates through the development pipeline.

• Data Analysis & Reporting: Analyze experimental data, prepare detailed reports, and present findings to internal stakeholders and external collaborators.

• Regulatory Compliance: Ensure all research activities comply with relevant regulatory guidelines and company policies.

Qualifications

• Education: Ph.D. in Pharmacology, Medicinal Chemistry, Neuroscience, or a related field.

• Experience: At least 2 years of postdoctoral or industry experience in drug discovery and development.

• Technical Skills: Proficiency in molecular biology techniques, cell-based assays, and animal models.

• Knowledge: Strong understanding of ion channel pharmacology, with a focus on Panx1 channels being highly desirable.

• Communication: Excellent written and verbal communication skills, with the ability to present complex data clearly and effectively.

• Teamwork: Demonstrated ability to work collaboratively in a multidisciplinary team environment.

Benefits

• Competitive salary and equity package.

• Comprehensive health, dental, and vision insurance.

• Generous paid time off and holiday schedule.

• Opportunities for professional development and career advancement.

• Collaborative and inclusive work culture.